Analgesic Therapyincreasesthe Risk Of Tramadol Dependence

Recommendations for use


Prolonged use of this opiate for analgesic therapyincreasesthe risk of Tramadol dependence. This is the reason, why three months is the maximum recommended duration of course with this analgesic. Patients with a history of alcohol or drug dependence should take precautions during the Tramadol course.




Tramadol should not be taken in intoxication with other opioid analgesics, alcohol or tranquilizers. The list of Tramadol contraindications also includes:


  • convulsive syndrome
  • acute airway obstruction
  • severe liver or kidney disease
  • mechanical or functional intestinal obstruction
  • cerebrovascular disease or injury
  • inflammation of the appendicitis or pancreas


Tramadol is not recommended for pain relief in children younger than 12 years of age or pregnant women. However, Tramadol can be used during pregnancy when the expected benefit from this painkiller exceeds any potential risks.




The results of comparative studies confirm that Tramadol has a less pronounced analgesic effect than Morphine, and a more favorable safety profile. The advantage of Tramadol vs Morphine is that it does not contribute to the increase of histamine in the body.


To date, Tramadol is one of the most popular drugs for the treatment of pain syndrome. It has a high analgesic activity, and helps to quickly eliminate or reduce the intensity of chronic or acute pain.


This psychotropic opioid analgesic is produced under different brands. In pharmacies, Tramadol is available under such popular brands as Durela, Ralivia, Tramal, Ultram, Maxitram, Tilodol, Larapam, Mabron, and Brimisol.


Tramadol is supplied to the world pharmaceutical market by various companies. The largest distributors of Tramadol are Sandoz, Valeant, Apotex, Cipher, Taro, Paladin, Janssen, Purdue, Seqirus, Arrow, and Generic Health.


Tramadol can be purchased through a program of preferential drug provision. In pharmacies, this opioid analgesic is sold by prescription. However, you can buy Tramadol analgesicswithout a prescriptionin some online pharmacies.